Three regions including Mtwara, Lindi and Ruvuma constitute this zone. The zonal headquarters are located in Mtwara. Residents of this zone are mostly producers of cashewnuts but the zone also boasts of high volumes of natural gas. All these activities require effective systems to enhance adherence to safety and health laws, regulations and standards for the health and safety of people engaged in such important economic ventures. Other activities carried out in the zone are trade and manufacturing.